despondent (adj.)
- apathetic
- bleak
- blue
- cheerless
- comfortless
- dashed
- dejected
- depressed
- despairing
- desperate
- disconsolate
- discouraged
- disheartened
- dismal
- dispirited
- down
- downcast
- downhearted
- drooping
- droopy
- forlorn
- grieving
- grim
- heartless
- hopeless
- hypochondriac
- hypochondriacal
- low
- low-spirited
- melancholy
- miserable
- morose
- mourning
- pessimistic
- sad
- sorrowful
- spiritless
- subdued
- suicidal
- unhappy
- unhopeful
- woebegone
- world-weary