irked (?.)
- aggravated
- angry
- annoyed
- anxious
- beset
- blase
- bothered
- browned-off
- bugged
- burnt-up
- chafed
- dispirited
- distressed
- disturbed
- embarrassed
- exasperated
- fed-up
- galled
- good and tired
- griped
- harassed
- inconvenienced
- irritated
- jaded
- life-weary
- melancholic
- melancholy
- miffed
- nettled
- peeved
- perturbed
- piqued
- plagued
- provoked
- put to it
- puzzled
- resentful
- riled
- roiled
- ruffled
- satiated
- sick
- sick of
- sore beset
- splenetic
- tired
- tired of
- tired of living
- tired to death
- troubled
- vexed
- wearied
- weariful
- weary
- weary unto death
- world-weary
- worried