anguished (adj.)

• aching
• anxious
• bored
• careworn
• cheerless
• cut
• depressed
• disgusted
• doleful
• dolorous
• grief-stricken
• grievous
• grim
• hurt
• injured
• joyless
• lamentable
• lugubrious
• mournful
• nauseated
• nauseous
• pained
• plaintive
• plangent
• rueful
• sad
• sorrowful
• sorrowing
• stung
• tearful
• uneasy
• unfulfilled
• ungratified
• unhappy
• unquiet
• unsatisfied
• woeful
• wounded