careworn (adj.)

• anguished
• distressed
• doleful
• dolorous
• drawn
• exhausted
• fagged
• grief-stricken
• grievous
• heavy-laden
• jaded
• lamentable
• lugubrious
• mournful
• pinched
• plaintive
• plangent
• rueful
• sorrowful
• sorrowing
• tearful
• troubled
• woeful
• worn