grievous (adj.)
- abominable
- acute
- affecting
- afflictive
- anguished
- appalling
- arrant
- atrocious
- awful
- base
- beastly
- bitter
- black
- blameworthy
- bleak
- brutal
- burdensome
- calamitous
- careworn
- cataclysmal
- cataclysmic
- catastrophic
- cheerless
- comfortless
- contemptible
- damaging
- dangerous
- demanding
- deplorable
- depressing
- depressive
- despicable
- destructive
- detestable
- dire
- disastrous
- disgusting
- dismal
- dismaying
- distasteful
- distressful
- distressing
- doleful
- dolorous
- dreadful
- dreary
- egregious
- enormous
- exacting
- exigent
- fatal
- fell
- fetid
- filthy
- flagrant
- foul
- fulsome
- galling
- grave
- grief-stricken
- gross
- harmful
- hateful
- heartbreaking
- heartrending
- heavy
- heinous
- horrible
- horrid
- hurtful
- infamous
- intolerable
- joyless
- lamentable
- loathsome
- lousy
- lugubrious
- major
- monstrous
- mournful
- moving
- nasty
- nefarious
- noisome
- notorious
- obnoxious
- odious
- offensive
- oppressive
- outrageous
- painful
- pathetic
- piteous
- pitiable
- pitiful
- plaintive
- plangent
- poignant
- rank
- regrettable
- reprehensible
- repulsive
- rotten
- rueful
- ruinous
- sad
- scandalous
- scurvy
- serious
- severe
- shabby
- shameful
- sharp
- shocking
- shoddy
- sordid
- sore
- sorrowful
- sorrowing
- squalid
- superincumbent
- taxing
- tearful
- terrible
- touching
- tough
- tragic
- ugly
- unbearable
- unclean
- uncomfortable
- unfortunate
- unpalatable
- vile
- villainous
- weighty
- woebegone
- woeful
- worst
- worthless
- wounding
- wretched