desperation (n.)

• acedia
• anguish
• anxiety
• anxiousness
• apathy
• defeatism
• dejection
• depression
• despair
• despondency
• disconsolateness
• discouragement
• distress
• foolhardiness
• forlornness
• gloom
• heedlessness
• hopelessness
• impetuosity
• imprudence
• melancholy
• misery
• pessimism
• rashness
• recklessness
• sloth
• sorrow
• wretchedness