disadvantageous (adj.)

• baleful
• baneful
• corrosive
• corrupting
• corruptive
• counterproductive
• damaging
• deadly
• deleterious
• depreciative
• depreciatory
• detrimental
• disparaging
• distressing
• harmful
• hurtful
• injurious
• lethal
• malefic
• malevolent
• malign
• malignant
• mischievous
• noisome
• noxious
• ominous
• pejorative
• pernicious
• poisonous
• prejudicial
• slighting
• toxic
• uncomplimentary
• unfavorable
• unprofitable
• unrewarding
• useless
• venomous
• vicious
• virulent
• worthless