fateful (adj.)
- acute
- apocalyptic
- appointed
- awe-inspiring
- bad
- baleful
- baneful
- black
- boding
- calamitous
- cataclysmal
- cataclysmic
- catastrophic
- certain
- conclusive
- consequential
- consuming
- consumptive
- critical
- crucial
- dark
- deadly
- decisive
- destined
- destroying
- destructive
- determinative
- devastating
- devoted
- dire
- direful
- disastrous
- doomed
- dreary
- earnest
- evil
- fatal
- fated
- foreboding
- formidable
- gloomy
- grave
- heavy
- ill
- ill-fated
- ill-omened
- ill-starred
- important
- imposing
- inauspicious
- indefeasible
- ineluctable
- inescapable
- inevitable
- inexorable
- inflexible
- internecine
- irresistible
- irrevocable
- lethal
- lowering
- major
- marked
- menacing
- momentous
- necessary
- nihilistic
- ominous
- ordained
- pivotal
- portentous
- ravaging
- relentless
- resistless
- ruinous
- self-destructive
- serious
- significant
- sinister
- sober
- solemn
- somber
- subversive
- suicidal
- sure
- threatening
- unavoidable
- uncontrollable
- unfavorable
- unfortunate
- unlucky
- unpreventable
- unpromising
- unpropitious
- unstoppable
- untoward
- unyielding
- wasteful
- weighty
- withering
- written