nuisance (n.)

• aggravation
• annoyance
• ass
• bedevilment
• bore
• bother
• botheration
• burden
• devilment
• difficulty
• downer
• drag
• drip
• exasperation
• harassment
• hassle
• headache
• humdrum
• inconvenience
• irritant
• irritation
• molestation
• nag
• ordeal
• persecution
• pest
• pesterer
• pill
• plague
• problem
• tease
• tormenter
• tormentor
• trial
• trouble
• twaddler
• vexation
• worriment
• worry