disadvantage (n.)
- abuse
- ado
- annoyance
- anxiety
- bar
- blight
- blocking
- bother
- burden
- burthen
- cargo
- charge
- cross
- cumbrance
- curse
- damage
- defect
- defile
- deprivation
- detriment
- difficulty
- disability
- disservice
- distress
- doom
- drawback
- embarrassment
- encumbrance
- evil
- fault
- flaw
- freight
- hamper
- handicap
- harm
- headache
- hex
- hindrance
- hurt
- impairment
- impediment
- impedimenta
- imposition
- inconvenience
- injury
- jinx
- liability
- load
- loss
- lumber
- matter
- menace
- mischief
- obstacle
- obstruction
- onus
- outrage
- pack
- penalty
- poison
- prejudice
- problem
- savage
- scathe
- shortcoming
- taint
- torment
- torture
- trouble
- weakness
- weight
- worry
- wound
- wrong
disadvantage (v.)
- abuse
- ado
- afflict
- aggrieve
- bar
- befoul
- bewitch
- blight
- bother
- burden
- burthen
- charge
- condemn
- corrupt
- cross
- crucify
- curse
- damage
- defect
- defile
- deprave
- despoil
- destroy
- discommode
- disoblige
- distress
- doom
- envenom
- evil
- fault
- flaw
- freight
- hamper
- handicap
- harass
- harm
- hex
- hurt
- impair
- incommode
- inconvenience
- infect
- injure
- jinx
- load
- loss
- lumber
- maltreat
- matter
- menace
- mistreat
- molest
- outrage
- pack
- persecute
- poison
- pollute
- prejudice
- savage
- taint
- threaten
- torment
- torture
- trouble
- violate
- weight
- worry
- wound
- wrong