malaise (n.)
- abnormality
- affection
- affliction
- agitation
- ailment
- allergy
- angst
- anguish
- anxiety
- anxiousness
- apprehension
- apprehensiveness
- atrophy
- blight
- bluster
- boil
- boiling
- boredom
- brouhaha
- bustle
- care
- cheerlessness
- churn
- commotion
- complaint
- complication
- concern
- condition
- debility
- decrepitude
- defect
- deformity
- dejectedness
- dejection
- depression
- despair
- despondency
- disability
- discomfort
- discomposure
- discontent
- discouragement
- disease
- disheartenment
- dislike
- disorder
- dispiritedness
- displeasure
- disquiet
- disquietude
- dissatisfaction
- distemper
- distress
- disturbance
- dolor
- downer
- downheartedness
- dread
- dullness
- ebullition
- embroilment
- emptiness
- endemic
- ennui
- excitement
- fear
- feebleness
- ferment
- fermentation
- fever
- feverishness
- flap
- flatness
- flurry
- fluster
- foreboding
- fume
- fuss
- grimness
- handicap
- heartlessness
- hopelessness
- hubbub
- hurt
- hurting
- illness
- indisposition
- infirmity
- inquietude
- jitters
- joylessness
- jumpiness
- lowness
- maelstrom
- malady
- misery
- misgiving
- moil
- morbidity
- morbus
- nausea
- nervousness
- oppression
- overanxiety
- pain
- painfulness
- pathology
- perturbation
- pessimism
- pucker
- restlessness
- rockiness
- roil
- rout
- row
- savorlessness
- seediness
- sickness
- solicitude
- spiritlessness
- spleen
- staleness
- stew
- stir
- strain
- suffering
- suspense
- swirl
- syndrome
- tastelessness
- tediousness
- tedium
- tension
- to-do
- trepidation
- trepidity
- trouble
- tumult
- turbidity
- turbulence
- turmoil
- uncomfortableness
- unease
- uneasiness
- unhappiness
- unhealthiness
- unrest
- upset
- vexation
- zeal